The New York Jets waived Isaiah Williams on Saturday, just days after the return specialist fumbled on a second-half kickoff in Monday night's 27-21 loss to the Miami Dolphins.

• "That was a big part of the game, and I let the team down," Williams said postgame.

  That wasn't Williams' only gaffe of the loss, as he also made a fair catch on his own 3-yard line with New York facing an 11-point fourth-quarter deficit.

  "Just thinking too much, man, just trying to make a play," he said about the fair catch. "At the last minute, I see (a Miami player), and I forget where I am on the field."

  Williams is the second Jets special teams player to be cut in four weeks. New York waived Xavier Gipson after he fumbled the ball late in a two-point loss in Week 1 to the Pittsburgh Steelers.

  Running backs Avery Williams and Isaiah Davis could take over return duties for the Jets in Sunday's game against the Dallas Cowboys. Williams was signed to the practice squad this week and elevated to the active roster on Saturday. He has over 100 career combined kick and punt returns, while Davis has 11 kickoff returns this season.

  The Jets also downgraded their No. 1 kickoff returner, Kene Nwangwu, on Saturday. He will miss his fourth straight game due to a hamstring injury.

  New York signed linebacker Mykal Walker from the practice squad and elevated safety Dean Clark to the active roster.

  The Jets are looking for their first win of the season on Sunday.

  --Field Level Media

The New England Patriots activated linebacker Jahlani Tavai off injured reserve on Saturday, and he is expected to make his season debut on Sunday night against the Buffalo Bills.

• Tavai has been sidelined with a calf injury sustained in June. He briefly attempted to practice at the outset of training camp before being placed on IR and missing the first four games of the season.

  Tavia, 29, was New England's leading tackler last season with a career-best 115 stops. He racked up 110 in 2023.

  Patriots coach Mike Vrabel indicated Friday that he was excited about getting Tavia back on the field after the latter was listed as questionable on the injury report.

  "Versatility. I think he plays with good technique," Vrabel said, pointing out Tavia's strengths. "I think he can play multiple spots. I think he's an instinctive player. I think he sees the field. I think he understands different concepts. He's a veteran player who's played in multiple spots."

  Tavia has 424 tackles, 5.5 sacks, five forced fumbles, four interceptions and two fumble recoveries in 95 NFL games (60 starts) with the Detroit Lions (2019-20) and Patriots.

  New England also downgraded linebacker K'Lavon Chaisson (knee) to out on Saturday. Chaisson was listed as questionable on Friday.

  Chaisson has nine tackles and 2.5 sacks in four games this season. The 26-year-old is in his first season with the Patriots after playing four seasons with the Jacksonville Jaguars (2020-23) and last season with the Las Vegas Raiders.

  --Field Level Media

Former NFL quarterback and current Fox Sports analyst Mark Sanchez was arrested in an Indianapolis hospital on Saturday after being stabbed in the chest in an early-morning incident in the city.

• The Indianapolis Metropolitan Police Department said Sanchez, 38 -- who retired from the NFL after the 2018 season -- was charged with misdemeanor counts of battery with injury, unlawful entry of a motor vehicle and public intoxication. He remained hospitalized Saturday evening and had not yet been booked into the Marion County Adult Detention Center.

  Earlier Saturday, Fox Sports said Sanchez was in stable condition. He was in Indianapolis to call Sunday's game between the host Colts and Las Vegas Raiders at Lucas Oil Stadium.

  The New York Post, citing a police report, said Sanchez was charged in connection with a bloody brawl outside a downtown Indianapolis bar with a 69-year-old delivery driver, who wound up stabbing the former Jets star in the chest in what the driver said was self defense.

  The violence allegedly started when Sanchez confronted the driver in an alley outside Loughmiller's Pub & Eatery shortly after midnight and told the driver to move his car, the Post reported, per Fox59/CBS4.

  The driver, who was dropping off a food order, told police that Sanchez became aggressive, forcing him to fight in self-defense with a knife after pepper spray didn't stop the ex-quarterback, the Post reported, citing the TV outlet.

  Police said both men were injured during the altercation. The driver, who had not been identified publicly, suffered "significant injuries."

  According to the Post, sources told Fox59/CBS4 that Sanchez was not cooperative with officers on the scene. After being hospitalized, he underwent surgery for his stab wounds.

  "We are deeply grateful to the medical team for their exceptional care and support," Fox Sports said.

  Sanchez, 38, was selected by the New York Jets with the fifth overall pick of the 2009 NFL Draft and guided the club to two straight AFC Championship Game appearances. He posted a 37-36 record and threw for 15,357 yards with 86 touchdowns and 89 interceptions with the Jets, Philadelphia Eagles, Dallas Cowboys and the Washington franchise.

  In college, Sanchez was a big star for Southern California in 2008 when he passed for 3,207 yards, 34 touchdowns and 10 interceptions. The Trojans went 12-1 and finished the campaign as the No. 3 team in the land.

  --Field Level Media

The Dallas Cowboys placed safety Malik Hooker on injured reserve Saturday with a toe injury.

• The Cowboys (1-2-1) also signed safety Alijah Clark to the active roster prior to Sunday's game against the host New York Jets (0-4), while wide receivers Jalen Brooks and Jalen Cropper were elevated from the practice squad.

  Hooker sustained the injury in the second quarter of Sunday night's game against the visiting Green Bay Packers.

  He has 20 tackles in four games (all starts) this season.

  Hooker, 29, has totaled 381 tackles, 14 interceptions and four fumble recoveries in 104 career games (80 starts) with the Indianapolis Colts and Cowboys. He was selected by the Colts with the 15th overall pick of the 2017 NFL Draft.

  --Field Level Media

Jacksonville Jaguars defensive end Travon Walker is expected to be a game-time decision on Monday night versus the visiting Kansas City Chiefs, head coach Liam Coen told reporters Saturday.

• "We're gonna go right down to the wire with it," Coen said. "I trust that if he says he can go, then we'll go."

  Walker underwent wrist surgery on the heels of sustaining the injury in Sunday's 26-21 win at San Francisco. He was back at practice on Saturday, wearing a cast/club on his left hand after missing Thursday and Friday's practices.

  Walker, 24, has recorded 2.0 sacks and 12 tackles in four games (all starts) this season.

  If Walker is cleared to play Monday, he could wear a protective brace and be under snap-count limitations.

  The fourth-year defensive end was the No. 1 pick in the 2022 draft out of Georgia. He also had surgery during his freshman season in October 2019 to repair a broken wrist but returned to play for the Bulldogs a few weeks later.

  The Jaguars picked up Walker's fifth-year option for the 2026 season worth $14.7 million.

  Walker has played in every game (38 consecutive starts) since the beginning of his second NFL season in 2023. He missed two games as a rookie and has compiled 26 sacks in 53 career regular-season games.

  --Field Level Media

Commanders star quarterback Jayden Daniels will be back in the starting role after a two-game injury absence when Washington visits the Los Angeles Chargers on Sunday.

• Daniels has been sidelined since sustaining a sprained left knee in Week 2 against the Green Bay Packers.

  Washington coach Dan Quinn told reporters on Friday that Daniels would be the starter. The team also released the news later on social media.

  Daniels was a full practice participant all week and will wear a brace on the knee on Sunday. He had badly wanted to return this week as he is from San Bernardino, located about 75 miles away from where the Chargers play in Inglewood.

  Daniels has passed for 433 yards and three touchdowns and rushed for 85 yards this season.

  Last season, Daniels was a force by completing 69 percent of his passes for 3,568 yards, 25 touchdowns and nine interceptions. He also rushed for 891 yards and six touchdowns, securing 55 first downs on 148 attempts while winning NFL Offensive Rookie of the Year honors.

  Marcus Mariota started the past two games for the Commanders (2-2). He passed for 363 yards, three touchdowns and one interception and added 60 rushing yards and one score.

  Washington will be without receivers Terry McLaurin (quadriceps) and Noah Brown (groin/knee). McLaurin is missing his second straight game and Brown will be sidelined for the third consecutive contest.

  Commanders guard Sam Cosmi (knee) also was ruled out.

  The Chargers will be without rookie tackle Joe Alt (ankle) and receiver Derius Davis (knee). Guard Mekhi Becton (concussion), and tight ends Will Dissly (knee) and Tucker Fisk (toe) are questionable.

  --Field Level Media

Arthur Jones, who played in parts of seven NFL seasons and won a Super Bowl title with the Baltimore Ravens, has died. He was 39.

• The Ravens announced Jones' passing in a social media post Friday afternoon. Other than to say his death was "sudden," the team did not reveal a cause or time of death.

  "We are terribly saddened to learn of Arthur Jones' sudden passing," Ravens executive VP and general manager Eric DeCosta said in a statement. "Arthur's presence was a gift to everyone he encountered. His big, bright smile, infectious energy and eternal positivity created a presence that continuously uplifted others.

  "He was kind, courteous and enthusiastic -- always displaying a love for family, teammates and friends."

  The Ravens selected Jones in the fifth round of the 2010 NFL Draft, and he played the ensuing four seasons for the franchise. He had a career-high 4.5 sacks in 2012, leading him to becoming a regular starter for the 2013 season, when he notched an additional four sacks in 14 games.

  Jones also recorded a sack and a fumble recovery in Super Bowl XLVII, when the Ravens defeated the San Francisco 49ers 34-31.

  Jones spent 2014 and 2016 with the Colts -- missing 2015 with an ankle injury. He played in one game for Washington in 2017 and finished his career with 173 tackles, 10 sacks and two forced fumbles in 64 games (31 starts).

  Jones was the older brother of former New England Patriots and Arizona Cardinals star Chandler Jones and retired UFC heavyweight champion Jon "Bones" Jones.

  --Field Level Media

Cincinnati Bengals quarterback Jake Browning will get a weapon back this week with tight end Noah Fant out of the concussion protocol and cleared to play Sunday against the Detroit Lions, head coach Zac Taylor said Friday.

• Fant, 27, was a full practice participant on Thursday for the first time since sustaining a concussion during Cincinnati's 48-10 loss to the Minnesota Vikings in Week 3. Despite missing one full game and a part of another, Fant's 12 catches this season are second-most on the Bengals and he has one of the team's five receiving touchdowns.

  Over 98 games (85 starts) across seven seasons, Fant has 3,385 receiving yards and 16 touchdown catches.

  In his first season with the Bengals (2-2), Fant could help to boost a passing game that has struggled since Joe Burrow went down with turf toe in Week 2. In the two full games without Burrow, Cincinnati has managed just 13 points and 265 passing yards with Browning at the helm.

  Wide receiver Charlie Jones (Achilles) is listed as questionable but did not practice all week while defensive end Shemar Stewart (ankle) will miss his third straight game Sunday vs. Detroit (3-1).

  --Field Level Media

Tennessee Titans running back Tyjae Spears and wide receiver Calvin Ridley are both questionable for Sunday's game at Arizona, coach Brian Callahan told reporters Friday.

• Ridley was back at practice Friday after missing Wednesday and Thursday with knee and elbow injuries. After posting 1,017 yards and four touchdowns in his first season in Tennessee and each of his last three full seasons, the veteran receiver, 30, has gotten off to a slow start, managing just 10 catches for 141 yards and no touchdowns in the first four games of the 2025 season.

  The Titans (0-4) have a league-worst 494 passing yards through Week 4 as No. 1 overall pick Cam Ward has struggled to generate production at the onset of his NFL career.

  Spears, 24, began the season on injured reserve after sustaining a high ankle sprain in the Titans' preseason opener. He returned to practice for the first time Wednesday but remains on IR with a questionable designation for Sunday's game.

  A third-round pick in the 2023 draft, Spears has rushed for 765 yards and six touchdowns in his first two seasons with Tennessee, averaging 6.3 yards per carry.

  Callahan also said offensive linemen JC Latham (hip) and Blake Hance (shoulder), wide receiver Bryce Oliver (knee) and safety Mike Brown (knee) have been ruled out .

  --Field Level Media

New Orleans Saints owner Gayle Benson has signed a new lease that will keep the Caesars Superdome as the team's home field through the 2035 season.

• Benson signed the lease with the Louisiana Stadium and Exposition District on Thursday after lengthy negotiations.

  "Discussions about this agreement have spanned two (state) administrations, a global pandemic and Hurricane Ida," Benson said. "I am totally happy that we will be sending a signed copy of this agreement to the NFL for their approval.

  "We have entered into numerous negotiations with the state, for as far back as I can recall. And each time, a better partnership has been formed with a clearer vision for mutual success for both the state and the team. But more importantly, for our fans. And I am convinced that today, this is the case."

  The Saints have played in the Superdome since 1975. The building has hosted eight of the 11 Super Bowl games played in New Orleans, and Benson said she intends to apply to host another one once the NFL signs off on the lease.

  Terms of the agreement were not released, but the team said the contract calls for continued capital improvements for the aging stadium.

  Benson, a New Orleans native, has no plans to move the team she inherited upon the death of her husband, Tom Benson. According to NOLA.com, her estate plan calls for the team to be sold after her death because she has no heirs. She is 78.

  Her estate calls for new owners to keep the team in New Orleans, but that cannot be guaranteed beyond the length of the lease.

  "To me, this Superdome and the Saints are not two different things; they are actually one," Gov. Jeff Landry said. "And in my opinion, that's why the Saints can never leave the city of New Orleans.

  "It never crossed my mind that we were not going to reach a deal. We wanted to make sure that the taxpayer was protected, that the citizens got a good deal and at the same time, we wanted to make sure that the Saints were made whole and that we gave them the incentive to stay here."

  --Field Level Media

The Carolina Panthers will turn to Rico Dowdle to handle the bulk of the ground attack after ruling out fellow running back Chuba Hubbard for Sunday's game against the visiting Miami Dolphins.

• Signed to a one-year, $2.75 million contract in the offseason, Dowdle will make his first start with Carolina as Hubbard deals with a calf injury that kept him out of practice this week.

  In addition to Hubbard, the Panthers (1-3) also ruled out tight end JaTavion Sanders (ankle), cornerback Chau Smith-Wade (chest) and defensive lineman Tershawn Wharton (toe) against Miami. Starting outside linebacker D.J. Wonnum (hip), defensive tackle Cam Jackson (knee) and defensive end LaBryan Ray (ankle) were listed as questionable.

  Hubbard, 26, also dealt with the calf issue last week but totaled 69 yards from scrimmage on 13 touches in a 42-13 loss at the New England Patriots. However, he did see a season-low 51 percent snap share as Dowdle rushed for 32 yards on nine carries.

  "We just couldn't get Chuba around quickly enough to put him out there,'' Panthers head coach Dave Canales said. "We'll keep working on him and take another look at him early next week. Rico, we're expecting him just like always to run the runs we call, and run with the type of energy and intensity we know he can.''

  Canales labeled Hubbard as day-to-day.

  Dowdle, 27, has rushed 28 times for 83 yards and a touchdown this season. He totaled a career-high 1,079 yards rushing in 2024 with the Dallas Cowboys.

  Third-string rookie Trevor Etienne has seen limited action, accumulating 33 yards on seven carries last Sunday and 37 yards on eight carries overall in four games.

  Signed to a four-year, $33.2 million contract late last season, Hubbard leads the Panthers in carries (53) and rushing yards (217) this campaign. He also has 13 catches for 94 yards and two touchdowns.

  --Field Level Media

Only the Detroit Lions and Buffalo Bills have more points than the Baltimore Ravens this season, so head coach John Harbaugh's critique of the approach and execution of play-caller Todd Monken at Kansas City raised a few eyebrows.

• Monken said he wasn't alarmed by anything Harbaugh said on the heels of the Ravens' third loss in four games, 37-20 to the Chiefs. The Ravens had a season-low 20 points, went 3 of 10 on third downs and 1 of 4 on fourth down in a game that ended with quarterback Lamar Jackson on the sideline nursing a hamstring injury.

  Now, the Ravens' offense will have to operate at least one full game without Jackson at the helm. After not practicing all week, Jackson will officially miss Sunday's game against the Houston Texans, per the team's Friday injury report. It'll be his first missed game due to injury since 2022, when he suffered a sprained knee and sat out the final five games of the regular season and the playoff loss to the Bengals.

  "There's not one thing John said that we didn't already talk about. Not one thing. So, there was nothing about it that I hadn't already heard or that he didn't already feel," Monken said Friday. "One thing I've done throughout my career is that you've got to look at what you do. How do we scheme it? What was our plan?

  "When it's below the line (expected), you have to own it and fix it. That's what you do. That's what we do as human beings. That's how I got to where I am now. You look at it, and you say, 'OK, was that good enough?' The expectation here is to be elite, and we've been elite. We're going to continue to be elite, but I have to do it better. We've got to do it better."

  The Ravens are third in the NFL with 131 points -- Detroit has 137, Buffalo 133 -- but have given up 133. A taxed defense is dealing with its own stack of injuries, with linebacker Roquan Smith (hamstring) and cornerbacks Marlon Humphrey (calf) and Chidobe Awuzie (hamstring) also out for this week's game. Safety Kyle Hamilton (groin) and linebacker Odafe Oweh (eye) are listed as questionable.

  At Kansas City, Harbaugh also said the Ravens didn't follow through on a team-wide game plan to handle the Chiefs' pass-rush pressure. Monken was working with a familiar call sheet, but Baltimore left tackle Ronnie Stanley (ankle), center Tyler Linderbaum (calf) functioning at reduced capacity and Jackson reportedly playing more than two quarters with a strained hamstring before hitting the bench in favor of Cooper Rush.

  "I already addressed it. We've already talked about it. We didn't execute the way we planned," Monken said.

  The Ravens have allowed 15 sacks in four games and Jackson was sacked seven times the last time Baltimore played at home in Week 3, a 38-30 loss to the Detroit Lions.

  Rush, 4-4 last season as Dak Prescott's injury replacement for the Cowboys, is 9-5 in his career as a starter. Monken said he and Rush have worked overtime to be ready for any instance when Jackson can't take the field.

  "As athletic as Coop is, some of those things are not going to look the same as Lamar," Monken said. "But that doesn't mean you can't still be effective and efficient."

  Sunday is the first of three consecutive home games for Baltimore. The Ravens play at home again next week, facing the Los Angeles Rams (3-2), before a bye in Week 7.

  --Field Level Media

New York Jets running back/kick returner Braelon Allen will miss eight-to-12 weeks with an MCL sprain, head coach Aaron Glenn said Friday.

• Allen was placed on injured reserve Thursday, three days after he sustained the injury in New York's 27-21 loss to the Miami Dolphins.

  Allen, 21, was hurt on a kickoff return in the second quarter after losing his first career fumble in the first quarter.

  "There are two different ways he can go about it," Glenn said of Allen's plans for recovery. "He could actually rehab this or he could have surgery and get it cleaned up. The rehab time would be exactly the same. That'll be a decision he and his agent have to make, and I'm not making that decision for him."

  Isaiah Davis has been used as the third-down back, but his role might expand to helping out behind starter Breece Hall on Sunday when the Jets (0-4) host the Dallas Cowboys (1-2-1).

  The Jets also signed running back Khalil Herbert, who has return experience. He was cut from the Seahawks' practice squad on Wednesday.

  Allen has 18 carries for 76 yards this season. He's averaging 25 yards on four kickoff returns.

  --Field Level Media

Tampa Bay Buccaneers running back Bucky Irving has been ruled out for Sunday's game against the host Seattle Seahawks, head coach Todd Bowles announced Friday.

• Per an ESPN report, Irving could also miss the team's Week 6 game against the visiting San Francisco 49ers on Oct. 5 as he deals with a sprain in his left foot.

  Irving, on crutches and wearing a walking boot earlier in the week, joined wide receiver Mike Evans (hamstring), safety Christian Izien (quadriceps) and cornerbacks Jamel Dean (hip) and Benjamin Morrison (hamstring) in sitting out practice on Friday. All five players were ruled out for Sunday's game versus the Seahawks (3-1).

  Rachaad White, Sean Tucker and undrafted rookie Josh Williams are expected to handle the rushing responsibilities on Sunday for Tampa Bay (3-1).

  Irving gained 165 yards from scrimmage and had a 72-yard touchdown catch in Tampa's loss to the Philadelphia Eagles last week. The injury occurred in the first half when he was tackled by Eagles linebacker Jihaad Campbell.

  Bowles had said on Wednesday that if Irving was "not out of the boot by Friday, more than likely he's not going to play."

  Irving has 430 yards from scrimmage in 2025, seventh in the NFL.

  White has 23 carries for 108 yards and one touchdown this season. He also has eight receptions for 34 yards.

  --Field Level Media

Minnesota Vikings (2-2) vs. Cleveland Browns (1-3)

• Sunday, 9:30 a.m. ET, London

  FanDuel odds: Vikings -3.5, Total 35.5

  Series Rewind: This is the first meeting between the teams since 2021, when Baker Mayfield and Nick Chubb led the Browns to a 14-7 win in Minneapolis.

  Inside Edge intel: The Vikings have allowed fewer than 350 total yards in five consecutive games, the longest active streak in the NFL.

  Juggling quarterbacks is nothing new to these franchises, who will start players who began the season as backups in Week 5. Rookie Dillon Gabriel will take over under center when Cleveland kicks off against the Vikings at Tottenham Hotspur Stadium. Browns coach Kevin Stefanski, previously offensive coordinator of the Vikings, decided to make the change after his team lost 34-10 against the Detroit Lions a week ago. He benched Joe Flacco, a 40-year-old veteran who leads the NFL in turnovers. In comes Gabriel, whom the Browns drafted at No. 94 overall, for a stern test against blitz-heavy Vikings defensive coordinator Brian Flores. Gabriel has appeared in two games in backup duty, completing three of his four passes for 19 yards and one touchdown. Minnesota is on the second leg of a two-week international tour that began with a 24-21 loss to the Pittsburgh Steelers in Ireland last week. Carson Wentz is slated to make his third start of the season and has completed 66.7 percent of his passes for 523 yards with four touchdowns and two interceptions. He'll be operating behind a patchwork offensive line due to a long list of injuries. Rookie quarterback J.J. McCarthy is progressing from his high ankle sprain but is expected to remain out. Wentz has the confidence of Vikings coach Kevin O'Connell and the rest of the staff. Justin Jefferson is Wentz's clear-cut No. 1 target in the passing game. Jefferson has 22 catches for 326 yards and one touchdown in four games, which is considerably more than No. 2 target T.J. Hockenson, who has 13 catches for 115 yards and one touchdown.

  Houston Texans (1-3) at Baltimore Ravens (1-3)

  Sunday, 1 p.m. ET

  FanDuel odds: Texans -1.5, Total 40.5

  Series Rewind: The Ravens nearly pitched a Christmas Day shutout at Houston last season, winning 31-2. Baltimore also defeated the Texans in the postseason in January 2024, 34-10, and has won six of the past seven meetings.

  Inside Edge intel: Houston is 5-1 when passing for at least 250 yards since the 2024 season began. During the same timeframe, the Ravens have allowed 248.6 passing yards per game.

  Houston didn't get too wrapped up in whether or not Lamar Jackson's hamstring would keep him on the sideline this week, knowing the challenge runs deeper because of Baltimore's trove of weapons. RB Derrick Henry has 284 yards on the ground with three touchdowns and plowed through Houston's run defense 27 times for 147 yards and a touchdown on Christmas Day when these teams last met. Cooper Rush was 4-4 last season with the Dallas Cowboys, throwing the ball well on play-action but rarely attacking defenses over the top the way Jackson can with a subtle snap of the wrist. But Jackson is far from the only notable player who is out or questionable for Sunday's game. Cornerbacks Marlon Humphery (calf) and Chidobe Awuzie (hamstring) plus linebacker Roquan Smith (hamstring) will also miss the game against Houston. Safety Kyle Hamilton (groin), left tackle Ronnie Stanley (ankle) and receiver Devontez Walker (oblique) are questionable.

  The Texans blanked the Titans last week to win for the first time this season and don't want to drop a fourth game with Indianapolis and Jacksonville going strong atop the AFC South. They might have found something in RB Woody Marks, who tallied 118 yards from scrimmage and scored two TDs last week. Houston is trying to open up the passing game with WR Nico Collins, but pass protection hasn't been perfect. The Ravens are banged up on defense, too, but Baltimore sacked QB C.J. Stroud five times in the meeting last season. Stroud threw a pick and had a QB rating of 59.2.

  Las Vegas Raiders (1-3) at Indianapolis Colts (3-1)

  Sunday, 1 p.m. ET

  FanDuel odds: Colts -6.5, Total 47.5

  Series Rewind: Sunday's winner seizes the lead in a series knotted at 11-11, including a 1-1 split in the playoffs. The Colts have momentum with three wins in the last four meetings. Eight of the last 10 were decided by eight or fewer points.

  Inside Edge intel: The Colts have a point differential of plus-16 in the first quarter this season. Las Vegas allowed a touchdown in the first quarter in three of its first four games.

  This week's sudden retirement of decorated Colts cornerback Xavien Howard removes at least one threat facing Raiders quarterback Geno Smith, who tossed three of his NFL-leading seven interceptions in last weekend's painful 25-24 setback against the Bears. He also threw two touchdown passes to Ashton Jeanty, whose historic day against Chicago made him just the third rookie running back in NFL history with 100-plus rushing yards, one rushing TD and two TD catches in a game. He also leads the league with 15 broken tackles. TE Brock Bowers (knee) didn't practice all week and his absence would be considerable for a Raiders' team not built to match the Colts punch for punch. Losing Howard hurts, but Indy's best defense is an offense that ranks fourth in the NFL with 30.8 points per game behind a resurgent Daniel Jones (third in NFL with 1,078 passing yards). Jonathan Taylor has 100-plus scrimmage yards and a rushing TD in all four career games against the Raiders. He's also averaging more than 3.0 yards after contact, and the Raiders are among the NFL's worst in racking up missed tackle. Colts first-round pick Tyler Warren leads all tight ends with 263 receiving yards and all rookies with 19 catches. Warren and big WR Michael Pittman (23 receptions) are forming a dynamite 1-2 punch for Jones.

  Denver Broncos (2-2) at Philadelphia Eagles (4-0)

  Sunday, 1 p.m. ET

  FanDuel odds: Eagles -4.5, Total 43.5

  Series Rewind: Philadelphia has won three of the past four meetings to lead 9-5 in the all-time series. Two of their last three clashes saw the winner put a 50-piece on the board: The Broncos won 52-20 in 2013, and the Eagles won 51-23 in 2017.

  Inside Edge intel: The Broncos are 2-8 since the start of the 2024 season when allowing 100-plus rushing yards.

  The X's and O's will be flying in this showdown of veteran play-callers, as Sean Payton's Denver offense will attempt to find cracks in Vic Fangio's defense in Philadelphia. Arkadelphia-born quarterback Bo Nix and the Broncos racked up a season-high 512 yards in Monday's 28-3 beating of the Bengals, while the Eagles have yet to allow more than 376 in a game. Philadelphia has held each of its first four opponents to two touchdowns. Jalen Hurts and Co. have not lost at home since Week 2 last season and haven't lost to an AFC foe at home since Nov. 7, 2021 (Chargers). The defending champs are trying to start 5-0 for the third time in four seasons. They'll try to get Saquon Barkley and A.J. Brown going against a Denver defense led by All-Pro corner Pat Surtain II and ex-Eagle LB Alex Singleton, who has 32 tackles in his last three games.

  Dallas Cowboys (1-2-1) at New York Jets (0-4)

  Sunday, 1 p.m. ET

  FanDuel odds: Cowboys -2.5, Total 47.5

  Series Rewind: Dallas won the last meeting 30-10 at home in 2023 after the Jets won the previous three matchups.

  Inside Edge intel: The Cowboys are worst in the NFL preventing touchdowns to wide receivers: 1.4 per game since the start of the 2024 season.

  The Jets are one of three teams buried under a 0-4 start and are the only squad in the league not to force a turnover. First-year coach Aaron Glenn may have earned raves in the past as a defensive coordinator but his team is tied for 28th in scoring defense (30.0) and ranks last with a minus-7 turnover ratio. QB Justin Fields has gone five consecutive games without throwing an interception and is a threat to run, which presents a new challenge to Dallas' drop zone defense. The Cowboys also having plenty of trouble stopping teams, ranking last in total defense (420.5 yards per game) and 31st in scoring defense (33.0 points). Maybe missing that Micah Parsons guy? Dallas' Dak Prescott leads the NFL with 1,119 passing yards while throwing six touchdowns against three interceptions. He might need some introductions with as many as four starting offensive linemen out this week. LG Tyler Smith hasn't been on the field since the overtime tie with the Packers and is a game-time decision due to a knee injury. LT Tyler Guyton (concussion), RG Tyler Booker (ankle) and C Cooper Beebe, on IR with an ankle injury, put Dallas in a pickle against the Jets' strong front seven. Wide receiver George Pickens has 21 catches for 300 yards and four touchdowns and was a top target for Prescott with CeeDee Lamb (ankle) sidelined for last Sunday's 40-40 tie with the Green Bay Packers. New York's Breece Hall (238 rushing, 108 receiving) is solid but backup Braelon Allen (knee) was placed on injured reserve after being hurt in Monday's 27-21 loss at Miami. Star wideout Garrett Wilson has 27 receptions for 311 yards and one touchdown.

  New York Giants (1-3) at New Orleans Saints (0-4)

  Sunday, 1 p.m. ET

  FanDuel odds: Saints -1.5, Total 41.5

  Series Rewind: The Saints have won three of their last four and seven of the last 10 against the Giants, but New York holds a 17-16 lead in the all-time series.

  Inside Edge intel: The Giants have lost 14 consecutive games when trailing at halftime, all in the past two seasons.

  Fresh off becoming the first NFL QB since 2002 to win his first career start against a team with a 3-0 record or better, Jaxson Dart now leads the Giants into his first road start at winless New Orleans. Dart wasn't particularly productive in his first career start but was quite effective, throwing for 111 yards and a touchdown, running for 54 and a score and leading a turnover-free offensive performance. Giants NT Trevor Lawrence (illness) is questionable but is expected to play. Safety Tyler Nubin (groin) is a game-time decision. With another sack last week, Giants defensive end Brian Burns already has five on the season, his seventh straight season with five-plus sacks. New Orleans QB Spencer Rattler is hoping to snap an 0-10 skid as a starter to begin his NFL career, tied for the sixth-longest streak in NFL history. The Saints passed on Dart with the ninth overall pick, winding up with Tyler Shough, who lost a QB battle to Rattler, in the second round of this year's draft. With two more catches, Saints RB Alvin Kamara (586 career catches) can leap into the top five in NFL history in catches by a running back. The Saints listed QB-TE Taysom Hill (knee) as questionable to make his season debut after opening his return-to-practice window.

  Miami Dolphins (1-3) at Carolina Panthers (1-3)

  Sunday, 1 p.m. ET

  FanDuel odds: Dolphins -1.5, Total 44.5

  Series Rewind: This will be the first matchup of these teams in Charlotte since a 45-21 Panthers win in 2017. The Dolphins have won the two games since by a combined margin of 75-31 and lead the series 6-2.

  Inside Edge intel: In 13 games with at least one turnover the past two seasons, the Dolphins are 3-10.

  Miami plays its first game without star receiver Tyreek Hill, out for the season with dislocated knee and multiple torn ligaments sustained in Monday's win over the Jets, this weekend at Carolina. There's optimism about how Jaylen Waddle (4,314 yards and 22 catches in five seasons) can replace Hill's production. Tight end Darren Waller could also help out after recording two touchdown catches in his first game back from a one-year retirement. Carolina followed up a convincing win over Atlanta with a 42-13 dud of a loss last week at New England. Bryce Young is looking for his third straight interception-free start after throwing three in the first two games of the season, but he also ranks 31st out of 33 eligible QBs in yards per pass attempt (5.2). He keeps building chemistry with Tetairoa McMillan, who ranks second among rookies in receiving yards (278) and catches (18) but is still looking for his first career touchdown. But he'll be trying to strengthen his bond with Rico Dowdle, who jumps into the starting role at running back with Chuba Hubbard (calf) out. LB D.J. Wonnum (hip) and DT Cam Jackson (knee) are questionable for Carolina.

  Tampa Bay Buccaneers (3-1) at Seattle Seahawks (3-1)

  Sunday, 4:05 p.m. ET

  FanDuel odds: Seahawks -3, Total 44.5

  Series Rewind: Tampa Bay has lost its last two games at Seattle, last winning there in 2009. The Seahawks lead the series 9-6, but the Buccaneers have won five of the last seven.

  Inside Edge intel: Seattle has allowed one rushing touchdown in the past 11 games. The Seahawks have prevented a rushing TD on 128 consecutive drives, best in the NFL.

  Tampa Bay nearly pulled off its fourth straight comeback victory to begin the season, but dug itself too big a hole after falling behind 24-3 vs. Philadelphia last week, losing 31-25. QB Baker Mayfield has been exceptional on the road of late, throwing two-plus touchdowns in each of his last four road starts. However, he may be down a few weapons for this game at Seattle. Mike Evans (hamstring) and RB Bucky Irving (237 rushing yards, 193 receiving yards), who is dealing with foot and shoulder injuries, are both out. The Buccaneers do possess the NFL's longest active streak with 100-plus rushing yards in 13 consecutive games, but it's likely up to Rachaad White to continue it. The Seahawks have allowed less than 100 rushing yards in each of their past three games. Seattle is coming off a mini-bye after beating Arizona on a last-second field goal last Thursday. The Seahawks have won three straight games since losing their season opener. WR Jaxon Smith-Njigba is one of just two players with 90-plus scrimmage yards in all four games this season and RB Kenneth Walker has five carries for 15-plus yards. Seattle's defense ranks sixth with 12 sacks, including six in the Arizona win. The wider window for prep was not enough for the Seahawks to deem CB Devon Witherspoon (knee) and S Julian Love (hamstring) ready. They'll both miss the game along with OLB DeMarcus Lawrence, who left last week's win with a quadriceps injury. However, rookie S Nick Emmanwori, out the past three games with an ankle injury, was cleared for Week 5.

  Tennessee Titans (0-4) at Arizona Cardinals (2-2)

  Sunday, 4:05 p.m. ET

  FanDuel odds: Cardinals -8.5, Total 41.5

  Series Rewind: Kyler Murray threw four touchdown passes and rushed for a score in the most recent matchup, the Cardinals' 38-13 win in Nashville in 2021.

  Inside Edge intel: Arizona's Trey McBride has been targeted more than any tight end in the NFL -- 9.1 times per game -- since the start of the 2024 season.

  The Titans are one of three 0-4 teams in the NFL and have been outscored by a staggering 69 points. Rookie quarterback Cam Ward sharply criticized the team after Tennessee was outclassed 26-0 by the Houston Texans last week. The Titans had just 175 offensive yards and Ward set season lows for completion rate (38.5 percent) and passing yardage (108). It has been a bumpy start for the No. 1 overall pick. Ward is completing a league-worst 51.2 percent of his throws (among qualifiers) for 614 yards with two touchdowns and two interceptions. Lead receiver Calvin Ridley (knee/elbow) is questionable and Ward still doesn't have his ideal offensive line available. JC Latham (hip) and Blake Hance (shoulder) are out. Arizona dropped consecutive games by four total points to NFC West rivals San Francisco and Seattle the past two weeks. The Cardinals overcame a 14-point deficit against the Seahawks before falling on a field goal as time expired. Cardinals receiver Marvin Harrison Jr. caught six passes for 66 yards and one TD in that contest but also had a ball roll off his hands into those of Seattle's Ernest Jones IV for an interception. The Cardinals lost running back as Trey Benson (knee) and placed him on injured reserve after losing standout James Conner to a season-ending foot injury in the previous game. Either Michael Carter or Emari Demercado will start at RB on Sunday. Cardinals DL Darius Robinson (pectoral) is out and starting LG Evan Brown (hamstring) is out.

  Detroit Lions (3-1) at Cincinnati Bengals (2-2)

  Sunday, 4:25 p.m. ET

  FanDuel odds: Lions -10.5, Total 48.5

  Series Rewind: Cincinnati has won 10 of the past 11 games in the series.

  Inside Edge intel: Lions WR Jameson Williams is averaging 8.0 yards per catch this season, third in the NFL. The Bengals are 29th in the NFL, allowing an average of 5.4 yards after catch this season.

  Detroit is No. 1 in the NFL with 34.3 points per game as the Lions shrug off outside concern the offense might veer off the rails without coordinator Ben Johnson. QB Jared Goff leads the NFC with nine TD passes and has been pristine on the road with a completion percentage over 70 percent in nine of his last 10 road starts. The Cincinnati pass rush won't be full throttle without DE Shemar Stewart (ankle) this week. The Bengals are standing by Jake Browning at quarterback, but he's generated only one touchdown in eight quarters over the two starts since Joe Burrow's toe injury. Browning is 3-1 in four career starts at home. Turnovers are breaking the Bengals' backs -- Browning has thrown a pick for every 10.67 completions -- and holding off the Lions' pass rush headed by Aidan Hutchinson (4.0 sacks this season) is highest priority. Without time to throw, Browning risks continuing to be a target of WR Ja'Marr Chase's frustration. They've connected five times in each of Browning's starts this season but for a grand total of 73 yards.

  Washington Commanders (2-2) at Los Angeles Chargers (3-1)

  Sunday, 4:25 p.m. ET

  FanDuel odds: Chargers -2.5, Total 48.5

  Series Rewind: Different millennium, different results. The Chargers were 0-6 vs. Washington in the 20th century but are 5-1 since 2001, the only loss coming in overtime in 2013. Norv Turner coached Washington (1994-2000) and the Chargers (2007-12).

  Inside Edge intel: Since Jim Harbaugh was hired in Jan. 2024, the Chargers have 10 games with 120-plus rushing yards. Last week (161 rushing yards at Giants) was the first loss under Harbaugh in a game where the team rushing total was over 120.

  It's a California homecoming for Commanders quarterback Jayden Daniels, who grew up in San Bernardino and has been cleared to return after missing two games with a left knee injury. Washington managed a split in his absence with Marcus Mariota at the controls but will need Daniels at his best against a stingy Chargers defense that ranks third in the NFL, allowing 270.0 yards per game. The Washington D has been more generous, ranked 27th against the pass. That could be just the tonic Justin Herbert needs, as the L.A. QB has seen his completion percentage drop each week: 73.5 to 70.4 to 59.6 and down to 56.1 in last week's humbling loss to the previously winless Giants. Left tackle Joe Alt (ankle) and wide receiver Derius Davis (knee) were both ruled out for the Chargers, who are hopeful OG Mekhi Becton (concussion) can play after returning to practice Friday. Becton was out in the Week 4 loss to the Giants. And each team is rolling with a rookie running back. The Chargers elevated first-rounder Omarion Hampton (270 rushing yards, two TDs) to the starting role with Najee Harris on IR, and the Commanders are using a rotation led by seventh-round surprise Jacory Croskey-Merritt (172 rush yards, two TDs). Commanders WR Terry McLaurin is idle for the second consecutive week with a quadriceps injury.

  New England Patriots (2-2) at Buffalo Bills (4-0)

  Sunday, 8:20 p.m. ET

  FanDuel odds: Bills -8.5, Total 49.5

  Series Rewind: Buffalo has won eight of the past 11 meetings after New England won 35 of the previous 39 matchups.

  Inside Edge intel: The Bills have a streak of eight consecutive games over 100 rushing yards.

  Buffalo is one of two 4-0 teams and has racked up 133 points, second-highest in the league behind the Detroit Lions (137). The Bills are vying for their first 5-0 start since 1991, a season in which they reached the Super Bowl. Buffalo also is seeking its 15th consecutive regular-season homefield victory as the club continues to enjoy one of top atmospheres in the sport. Bills DT T.J. Sanders (knee) is questionable. CB Dorian Strong (neck) and LB Dorian Williams (knee) are out for the Bills. New England WR Stefon Diggs remembers Orchard Park well after spending four seasons - making the Pro Bowl each time - with the Bills. This will be his first trip in as a visiting player since he was traded to the Houston Texans following the 2023 campaign. Diggs had six catches for 101 yards in last week's 42-13 thumping of the Carolina Panthers. That also marked the first time New England reached the 40-point mark since 2021. Second-year quarterback Drake Maye is developing well and has completed 74 percent of his passes for 988 yards, seven touchdown and two interceptions. He also has rushed for two scores. Reigning NFL MVP Josh Allen of the Bills has thrown for 964 yards, seven touchdowns and one interception while also rushing for three scores. James Cook is the NFL's second-leading rusher with 401 yards and has a league-best five rushing touchdowns. New England allowed an opening-drive touchdown in three of its first four games. Four Patriots are listed as questionable: LB K'Lavon Chaisson (knee), CB Carlton Davis III (illness), LB Jahlani Tavai (calf) and DT Milton Williams (ankle).

  Kansas City Chiefs (2-2) at Jacksonville Jaguars (3-1)

  Monday, 8:15 p.m. ET

  FanDuel odds: Chiefs -3, Total 46.5

  Series Rewind: Kansas City has won the last eight games against Jacksonville, including a 27-20 playoff win in the 2023 divisional round.

  Inside Edge intel: The Chiefs are 11-0 when possessing the ball longer than their opponent the past two seasons. The Jaguars allowed an average time of possession of 32 minutes since the start of the 2024 season, second-highest in NFL.

  The Chiefs are back to .500 after their first 0-2 start in 11 years. Patrick Mahomes threw four touchdowns to four different players in last week's 37-20 win over Baltimore, more than the three TDs he threw in the first three games combined. Xavier Worthy, in his first game back from a dislocated shoulder, led the team in receiving (83) and rushing (38) yards. The Chiefs have turned the ball just once this season, something that will be tested by a Jaguars defense which leads the league in forced turnovers (13) and turnover differential (plus-nine). The only Chiefs player in danger of missing the game as of Friday's injury report was CB Kristian Fulton, who was a limited participant due to an ankle injury. The Jaguars are not certain if DE Travon Walker will be available days after a surgical procedure on his wrist, but head coach Liam Coen said this week he wasn't ready to rule him out. With a win last week at San Francisco, the Jaguars are 3-1 for just the second time in 15 years. After ranking 26th last season in rushing offense, Jacksonville ranks fourth under Coen, averaging 144.0 rushing yards per game. Travis Etienne Jr. is third in the NFL in rushing yards (394) and is averaging a league-best 6.1 yards per carry among players with 25 or more rushes. Four offensive linemen were limited as of Friday's workout in Jacksonville, which would be problematic facing Chiefs DT Chris Jones and DE George Karlaftis.

  --Field Level Media

San Francisco 49ers defensive tackle Kalia Davis is having surgery on Friday to repair a broken hand, NFL Network reported.

• Davis reportedly could miss at least two games after sustaining the injury in Thursday night's 26-23 overtime road win against the NFC West rival Los Angeles Rams.

  Davis, who turned 27 on Thursday, has started all five games for the 49ers (4-1) this season and contributed seven tackles with two tackles for loss.

  A sixth-round draft pick in 2022, Davis has recorded 20 tackles, one sack and one interception in 21 career games (five starts).

  --Field Level Media

The Indianapolis Colts added wide receiver Michael Pittman to their Week 5 injury report Thursday with a hamstring issue.

• Pittman was a limited participant in practice on Thursday ahead of Sunday's home game against the Las Vegas Raiders.

  The sixth-year pro caught five passes for 41 yards and a touchdown while playing his usual heavy allotment of snaps last weekend as the Colts (3-1) fell on the road to the Los Angeles Rams.

  Pittman is the top target for resurgent quarterback Daniel Jones. He has a team-high 21 receptions for 234 yards (11.1 per catch) and three scores.

  The Colts enter Week 5 with a plus-40 point differential that ranks fourth in the NFL. They're also fourth in points scored (30.8 per game) and net passing yards (261 per game).

  Indianapolis co-leads the AFC South with the Jacksonville Jaguars, who host the Kansas City Chiefs on Monday night.

  Defensive end Tyquan Lewis (oblique) also landed on Thursday's injury report. Veteran cornerback Xavien Howard abruptly retired for family reasons earlier in the week after starting each of the Colts' first four games.

  --Field Level Media

The Washington Commanders ruled out wide receivers Terry McLaurin and Noah Brown on Thursday for their road game Sunday against the Los Angeles Chargers.

• Both receivers missed a second day of practice on Thursday. McLaurin (quad) sat out last Sunday's game at Atlanta while Brown (groin/knee) has been sidelined for two games.

  Also ruled out was guard Sam Cosmi, who tore his ACL in the 2024 NFC divisional playoff game at Detroit and was designated on Wednesday to return to practice. The Commanders have 21 days from that point to return him to the active roster or place him injured reserve for the season.

  Wide receiver Deebo Samuel (heel) and cornerback Mike Sainristil (knee) missed their second consecutive day of practice. Linebacker Ale Kaho (concussion) was limited on Thursday after not participating on Wednesday, while defensive tackle Daron Payne (knee) was added to the injury report on Thursday as a limited participant.

  Defensive end Dorance Armstrong (illness) and linebacker Nick Bellore (quad/rest) were full participants after sitting out Wednesday's session.

  Safety Percy Butler (hip) was limited for the second straight day.

  Quarterback Jayden Daniels -- who was cleared to play this week after missing two games because of a knee injury sustained in Week 2 at Green Bay -- was a full participant, as were tight ends John Bates (calf/groin), who also was hurt against the Packers, and Colson Yankoff (ankle).

  --Field Level Media

The San Francisco 49ers have promoted quarterback Adrian Martinez from the practice squad to the active roster ahead of Thursday night's road game against the Los Angeles Rams.

• The 49ers (3-1) already had ruled out quarterback Brock Purdy (turf toe), making Mac Jones the starter against the Rams (3-1). Jones started in Weeks 2 and 3 when Purdy was sidelined. Jones injured a knee during Week 3 but is now healthy and was a full practice participant all week.

  Receivers Jauan Jennings (ankle/rib), Ricky Pearsall (knee) and Jordan Watkins (calf) and defensive end Robert Beal Jr. (ankle) also were declared out after not practicing this week.

  Martinez, 25, has not appeared in an NFL regular-season game. The 49ers signed him to their practice squad on Aug. 28 after he was waived by the New York Jets. He spent time on the Jets' practice squad in 2024 and also was in camp with the Detroit Lions in 2023.

  In other moves on Thursday, San Francisco elevated defensive lineman Trevis Gipson and wide receiver Malik Turner from the practice squad for game day, signed cornerback Derrick Canteen to the practice squad and waived defensive lineman Jordan Jefferson.

  Gipson, 28, was a fifth-round pick of the Chicago Bears in the 2020 NFL Draft. He has 81 career tackles, including 11 sacks, in 53 regular-season games (19 starts) for the Bears (2020-22), Tennessee Titans (2023) and Seattle Seahawks (2024).

  Turner, 29, has 29 career receptions for 414 yards and four touchdowns in 45 regular-season games (three starts) for the Seahawks (2018-19), Dallas Cowboys (2020-2021) and 49ers (2022, 2025).

  Jefferson, 24, was selected by the Jacksonville Jaguars in the fourth round of the 2024 draft. He played in one game this season for the 49ers and in eight for the Jaguars in 2024.

  Canteen signed with the 49ers in May as an undrafted free agent out of the University of Cincinnati. He also played at Virginia Tech (2023) and Georgia Southern (2019-22).

  --Field Level Media

Carolina Panthers running back Chuba Hubbard (calf) sat out his second straight practice on Thursday, putting his status for Sunday's home game against the Miami Dolphins in doubt.

• Two other starters, tight end Ja'Tavion Sanders (ankle) and defensive end Tershawn Wharton (toe), along with cornerback Chau Smith-Wade (chest), also missed practice on Thursday.

  Hubbard, 26, also dealt with the calf issue last week but totaled 69 yards from scrimmage on 13 touches in last Sunday's loss at the New England Patriots. However, he did see a season-low 51 percent snap share as backup Rico Dowdle rushed for 32 yards on nine carries.

  In his fifth season with Carolina since being drafted in the fourth round in 2021, Hubbard has rushed for a team-high 217 yards on 53 carries while notching 13 receptions for 94 yards and two scores in 2025. Overall, Hubbard has 3,392 rushing yards and 22 touchdowns on 808 carries along with 134 receptions, 843 receiving yards and four scores in 68 games (43 starts).

  Dowdle, who has rushed for 83 yards and a touchdown on 28 carries along with five receptions for 20 yards in four games this season, would likely start Hubbard is ruled out. Third-string rookie Trevor Etienne has seen limited action, accumulating 33 yards on seven carries last Sunday and 37 yards on eight carries overall in four games.

  --Field Level Media

The Baltimore Ravens' injury woes continued with safety Kyle Hamilton added to the list of players not practicing Thursday in advance of Sunday's home game against the Houston Texans.

• Hamilton, who is listed with a groin injury, had been limited in practice Wednesday.

  By time the full injury report was released Thursday, there were 14 Ravens players listed. Joining Hamilton as a new addition was linebacker Odafe Oweh, who was limited by an eye injury.

  Baltimore (1-3) has struggled with key injuries in the early part of the season. Among those who didn't practice Thursday, along with Hamilton, were quarterback Lamar Jackson (hamstring), fullback Patrick Ricard (calf), linebacker Roquan Smith (hamstring) and cornerbacks Marlon Humphrey (calf) and Chidobe Awuzie (hamstring).

  Along with Oweh, the limited participants were tackle Ronnie Stanley (ankle), wide receiver Devontez Walker (oblique), nose tackle Travis Jones (knee), cornerback Nate Wiggins (elbow) and rookie tackle Emery Jones, who is in the designated return-to-practice window from the IR as his shoulder injury heals up.

  There was some good news for the Ravens, with center Tyler Linderbaum (calf), defensive end Brent Urban (finger) and linebacker Kyle Van Noy (hamstring) practicing fully after being limited Wednesday.

  Cooper Rush is slated to start at quarterback for Baltimore should Jackson remain sidelined. Off the bench in the Ravens' 37-20 road loss Sunday to Kansas City, Rush completed nine of 13 passes for 52 yards without a touchdown or interception.

  Rush has started 14 of his 40 career games, including eight last season when he filled in for Dak Prescott with the Dallas Cowboys.

  --Field Level Media

The San Francisco 49ers travel to Los Angeles on Thursday night hoping an injury-riddled offense can hold up against the Rams' ninth-ranked defense.

• Los Angeles has produced 14 sacks and 20 tackles for loss through its 3-1 start. San Francisco also enters 3-1, but will turn to backup Mac Jones for a crucial NFC West matchup with quarterback Brock Purdy sidelined by his nagging turf toe injury.

  ODDS AND TRENDS

  The 49ers' offense will also be without wide receivers Jauan Jennings (ankle), Ricky Pearsall (knee) and Jordan Watkins (calf), with Brandon Aiyuk and tight end George Kittle already on injured reserve. That has led to the Rams being a consensus 9.0-point favorite as of Thursday afternoon.

  The line is 8.5 points at BetRivers, where 79 percent of the spread-line money is backing Los Angeles. The Rams' -500 moneyline has also drawn one-sided action with 88 percent of the total bets and 89 percent of the money.

  The Rams have won 15 of their past 16 games as favorites, while the 49ers have failed to cover the spread in 13 of their past 14 games against teams that entered with a winning record.

  PROP PICKS

  --Under 45.0 Total Points (-112 at BetRivers): Not only is the 49ers' offense decimated by injuries at the skill positions, but each of the Rams' past five games as home favorites have gone under the total points line.

  --Rams RB Kyren Williams Anytime TD (-175 at DraftKings): Williams has scored at least one touchdown in nine consecutive home games against NFC teams. For those looking for a bigger payout, Williams has scored the first TD in five of his past six home games -- and Williams scoring the first TD on Thursday is being offered at +360.

  RETURN OF THE MAC

  This will mark Purdy's third absence in four games due to the injury. He was initially hurt during a Week 1 contest against the Seattle Seahawks and aggravated the injury during last week's 26-21 home loss against the Jacksonville Jaguars.

  Jones started in Weeks 2 and 3 when Purdy was sidelined. Jones injured a knee during Week 3 but is now healthy and was a full practice participant all week.

  Jones is eager to take the field against the Rams' defense.

  "I think the way they play and their mindset," Jones said of what impresses him. "There are always 11 guys on the screen and they have a great defensive line. They play a lot of defense schemes.

  "It's going to be a challenge. I'm impressed with them so I can't wait to go against them."

  Purdy remained hopeful Tuesday but could see his hopes starting to slide.

  "I don't have as many days to get right and heal up and feel better," Purdy said.

  INJURY REPORT

  Along with Jennings, Pearsall and Watkins, 49ers defensive end Robert Beal Jr. (ankle) also was declared out after not practicing this week.

  San Francisco defensive lineman CJ West (thumb) is questionable. He was a limited participant on Wednesday.

  Tight end Tyler Higbee (hip) and offensive lineman Rob Havenstein (ankle) are listed as doubtful for the Rams. Neither player practiced this week.

  THEY SAID IT

  "I think they're a really well-rounded football team, always have been. When we play them, it's a bare-knuckles physical fight. They're gonna try to run the ball right at you, play-action it over the top, and on defense, they're gonna line up, know exactly what they're in and just try to out-physical you. So it's a big challenge for us, but a lot of credit to them because they've done a heck of a job with some injuries along the way early on." -- Rams quarterback Matthew Stafford, on facing the 49ers.

  PREDICTION

  San Francisco enters with the league's sixth-ranked defense, but 2.0 of the team's 5.0 sacks to date have come from now-injured defensive end Nick Bosa. Replacement Bryce Huff has 2.0 as well, but the 49ers will be hard-pressed to place the consistent pressure needed to generate the multiple turnovers its beleaguered offense desperately needs. --Rams 23, 49ers 16

  --Field Level Media

Jaguars defensive end Travon Walker is entertaining the idea of playing in an NFL game less than a week after surgery on his wrist.

• Jacksonville head coach Liam Coen revealed on Thursday morning that Walker underwent surgery after he was hurt in Sunday's 26-21 Week 4 win at San Francisco.

  Walker, who has 2.0 sacks and 12 tackles this season, was wearing a sling when he left Levi's Stadium with the team on Sunday night.

  "Saw a specialist on Monday, had a surgical procedure done, will be listed as day-to-day," Coen said of Walker. "And we'll update you guys per the injury report, just like every other player at the end of the day."

  Even if he's unable to practice, Coen said the door is not closed on Walker suiting up for the Jaguars in a home "Monday Night Football" matchup with the Kansas City Chiefs.

  If Walker, 24, is cleared to play Monday, he could wear a protective brace and be under snap-count limitations.

  The fourth-year defensive end was the No. 1 pick in the 2022 draft out of Georgia. He also had surgery during his freshman season in October 2019 to repair a broken wrist but returned to play for the Bulldogs a few weeks later.

  The Jaguars picked up Walker's fifth-year option for the 2026 season worth $14.7 million.

  Walker has played in every game (38 consecutive starts) since the beginning of his second NFL season in 2023. He missed two games as a rookie and has compiled 26 sacks in 53 career regular-season games.

  --Field Level Media

New York Jets running back Braelon Allen was placed on injured reserve with a sprained MCL on Thursday, three days after he injured his knee in a 27-21 loss to the Miami Dolphins.

• Allen served as the primary kickoff returner and short-yardage back for the Jets, helping spare Breece Hall in those situations as part of the NFL's third-ranked rushing offense (144.5 yards per game, 5.2 yards per carry).

  Allen, 21, was hurt on a kickoff return in the second quarter after losing his first career fumble in the first.

  Isaiah Davis has been used as the third-down back, but his role might expand.

  The Jets also signed running back Khalil Herbert, who has return experience. He was cut from the Seahawks' practice squad on Wednesday.

  The Jets (0-4) lost back-to-back games in Florida, 29-27 at Tampa Bay and the six-point loss to the Dolphins, and are at home to play the Dallas Cowboys (1-2-1) on Sunday. New York is looking to win for the first time under head coach Aaron Glenn.

  The Cowboys allowed 123.3 rushing yards per game in the first month of the season.

  Allen, who lost the fumble at the 1 at Miami in Week 4, has 18 carries for 76 yards this season. He's averaging 25 yards on four kickoff returns.

  Davis has five carries for 27 yards and three receptions for 24 yards.

  A sixth-round pick by the Bears in 2021, Herbert, 27, was traded to the Bengals in 2024 and spent the offseason on the Colts' roster. He was with Seattle's practice squad for less than two weeks.

  In 56 career games, Herbert has 400 carries for 1,905 (4.8 yards per carry) and nine touchdowns.

  Running back Kene Nwangwu would be a candidate to fill the return specialist spot but he was unable to practice Wednesday because of a hamstring injury.

  --Field Level Media

San Francisco 49ers quarterback Brock Purdy will miss Thursday night's showdown against the host Los Angeles Rams due to his turf toe injury.

• Purdy missed practice Wednesday for the third straight day.

  This will mark Purdy's third absence in four games due to the injury. He was initially hurt during a Week 1 contest against the Seattle Seahawks and aggravated the injury during last week's 26-21 home loss against the Jacksonville Jaguars.

  Mac Jones will draw the start for the 49ers (3-1). He started in Weeks 2 and 3 when Purdy was sidelined. Jones injured a knee during Week 3 but is now healthy and was a full practice participant all week.

  Receivers Jauan Jennings (ankle/rib), Ricky Pearsall (knee) and Jordan Watkins (calf) and defensive end Robert Beal Jr. (ankle) also were declared out after not practicing this week.

  Defensive lineman CJ West (thumb) is questionable. He was a limited participant on Wednesday.

  Purdy, 25, has completed 48 of 73 passes for 586 yards, with four touchdowns and four interceptions in his two games as a starter. Jones, 27, is 53-of-80 passing for 563 yards, with four scores and one pick while going 2-0 in his two starts.

  San Francisco will be shorthanded in terms of receiving targets as star tight end George Kittle (hamstring) is on injured reserve and standout receiver Brandon Aiyuk (knee) is still recovering from a serious knee injury sustained nearly 12 months ago.

  --Field Level Media