Tampa Bay 23, Atlanta 20
Baker Mayfield found rookie Emeka Egbuka for a go-ahead 25-yard touchdown pass with 59 seconds left on Sunday to propel the Tampa Bay Buccaneers to a 23-20 victory over the Atlanta Falcons.
Cincinnati 17, Cleveland 16
Joe Burrow was held to 113 yards passing, but two key Joe Flacco interceptions helped the Cincinnati Bengals hold on for their first season-opening win in four years, 17-16, over the Cleveland Browns on Sunday.
Indianapolis 33, Miami 8
Daniel Jones threw one touchdown pass and ran for two more in his Indianapolis debut to lead the host Colts to a comfortable 33-8 victory over the Miami Dolphins on Sunday.
Jacksonville 26, Carolina 10
The Jacksonville Jaguars began the Liam Coen era in resounding fashion Sunday, coasting to a 26-10 win over the visiting Carolina Panthers in the season opener for both teams.
Las Vegas 20, New England 13
New quarterback Geno Smith threw for 362 yards Sunday, rookie running back Ashton Jeanty scored the go-ahead touchdown, and visiting Las Vegas gave new coach Pete Carroll a win in his first game with the Raiders, stopping the New England Patriots 20-13 in Foxborough, Mass.
Arizona 20, New Orleans 13
Kyler Murray threw two touchdown passes and the visiting Arizona Cardinals spoiled Kellen Moore's debut as an NFL head coach with a 20-13 victory over the New Orleans Saints on Sunday afternoon.
Pittsburgh 34, N.Y. Jets 32
Chris Boswell kicked a career-long 60-yard field goal with 1:03 remaining to give the Pittsburgh Steelers a wild 34-32 victory over the New York Jets in the season opener for both on Sunday afternoon at East Rutherford, N.J.
Washington 21, N.Y. Giants 6
Jayden Daniels passed for 233 yards, rushed for 68 more and threw for one touchdown as the Washington Commanders opened their season with a 21-6 win over the visiting New York Giants.
Denver 20, Tennessee 12
Bo Nix threw for a touchdown, J.K. Dobbins ran for a score and the Denver Broncos' defense made life miserable for rookie quarterback Cam Ward in a season-opening 20-12 win over the visiting Tennessee Titans on Sunday.
San Francisco 17, Seattle 13
Backup tight end Jake Tonges caught a 4-yard touchdown pass from Brock Purdy with 1:34 remaining, helping the San Francisco 49ers rally to defeat the host Seattle Seahawks 17-13 Sunday afternoon.
Green Bay 27, Detroit 13
Jordan Love threw two touchdown passes and the host Green Bay Packers kept the Detroit Lions' potent offense out of the end zone until the final minute of a 27-13 victory Sunday in a season opener between teams expected to challenge for the NFC North title.
L.A. Rams 14, Houston 9
Matthew Stafford passed for 245 yards and a touchdown and a stifling defensive performance propelled the Los Angeles Rams to a 14-9 victory over the visiting Houston Texans on Sunday.
Buffalo 41, Baltimore 40
Matt Prater kicked a 32-yard field goal as time expired and the Buffalo Bills scored 16 unanswered points in the final 3:56 to register a dramatic 41-40 victory over the Baltimore Ravens in a season-opening AFC showdown on Sunday night at Orchard Park, N.Y.