| Player |
|
Status/Updated |
Notes |
| George Kittle
|
TE |
Ques Sept. 14 - Hamstring - 9/8/25 |
Kittle left the last game due to a hamstring injury, and it has yet to be established if he will be active against the Saints on Sunday, September 14th. |
| Jauan Jennings
|
WR |
Ques Sept. 14 - Shoulder - 9/8/25 |
Jennings exited the previous contest due to a left shoulder injury, and it has yet to be established if he will suit up against the Saints on Sunday, September 14th. |
| Mac Jones
|
QB |
Ques Sept. 14 - Knee - 9/7/25 |
Jones is hampered by a knee injury, and it remains to be seen if he will play on September 14 against the Saints. |
| Dominick Puni
|
OL |
Ques Sept. 14 - Knee - 9/7/25 |
Puni is battling an knee injury, and his availability for the September 14 against the Saints is unknown. |
| C.J. West
|
DT |
Ques Sept. 14 - Knee - 9/7/25 |
West is nursing with a knee injury, and it is unclear if he will be active on September 14 against the Saints |
| Nick Martin
|
LB |
Ques Sept. 14 - Lower Body - 9/7/25 |
Martin is hampered by a lower body injury, and it is unclear if he will be available for the September 14 against the Saints |
| Jordan Watkins
|
WR |
Ques Sept. 14 - Ankle - 9/7/25 |
Watkins is nursing with an ankle injury, and it is unclear if he will be active on September 14 against the Saints. |
| Jordan James
|
RB |
Ques Sept. 14 - Knee - 9/7/25 |
James is hampered by a knee injury, and it remains to be seen if he will play on September 14 against the Saints. |
| Ben Bartch
|
OL |
Ques Sept. 14 - Undisclosed - 9/7/25 |
Watkins is bothered by an undisclosed injury, and it is unclear if he will be active on September 14 against the Saints. |
| Ricky Pearsall
|
WR |
Ques Sept. 14 - Hamstring - 9/7/25 |
Pearsall has been shifted to the PUP list with a hamstring injury, leaving his status for the September 14 against the Saints up in the air. |
| Darrell Luter Jr.
|
CB |
Ques Sept. 14 - Pelvis - 9/7/25 |
Luter Jr. is battling a pelvis injury, and his availability for the September 14 against the Saints is up in the air. |
| Ji'ayir Brown
|
S |
Ques Sept. 14 - Ankle - 9/7/25 |
Brown is tending to an ankle injury, leaving his status for the September 14 against the Saints is uncertain. |
| Robert Beal Jr.
|
DL |
Ques Sept. 14 - Ankle - 9/7/25 |
Beal Jr. is managing an ankle injury, and it is unknown if he will be available for the game on September 14 against the Saints. |
| Ameer Abdullah
|
RB |
out for season - Ribs - 8/27/25 |
Abdullah has been placed on the season ending injured reserve due to a ribs injury. |
| Equanimeous St. Brown
|
WR |
out for season - Foot - 8/27/25 |
St. Brown has been placed on the season ending injured reserve due to a foot injury. |
| Jakob Robinson
|
CB |
out for season - Forearm - 8/28/25 |
Robinson is placed on the injured reserve list with a forearm injury, and he is projected to miss the remainder of the season. |
| Patrick Taylor Jr.
|
RB |
out for season - Shoulder - 8/20/25 |
Taylor Jr. has been added to the injured reserve list after he underwent season-ending surgery to repair a fracture in his shoulder, and has been shut down for the remainder of the season. |
| Tarron Jackson
|
DL |
Out indefinitely - Undisclosed - 7/29/25 |
Jackson is dealing with an undisclosed injury, and it is unclear how long he will be idle. |
| Jacob Cowing
|
WR |
Out Indefinitely - Leg - 8/28/25 |
Cowing has been designated for the injured reserve list due to a leg injury, and he will miss an undetermined length of time. |
| Malik Mustapha
|
S |
Out indefinitely - Knee - 8/28/25 |
Mustapha has landed on the PUP list while recovering from a torn acl, and a timetable for return has yet to be established. |
| Brandon Aiyuk
|
WR |
Out indefinitely - Knee - 8/28/25 |
Aiyuk is on the PUP list while recovering from knee surgery, and he will miss an extended period. |
| Kurtis Rourke
|
QB |
Out indefinitely - Knee - 8/28/25 |
Rourke has been shuttled to the NFI list with a knee injury, and he will miss an undetermined length of time. |
| Kevin Givens
|
DT |
Out indefinitely - Pectoral - 8/28/25 |
Givens is placed on the injured reserve list with a pectoral injury, and he will miss an extended period. |
| Trent Taylor
|
WR |
Out indefinitely - Undisclosed - 7/25/25 |
Taylor has been put on the injured reserve list with an undisclosed injury, and he is projected to miss the remainder of the season. |
| Tre Tomlinson
|
CB |
Out indefinitely - Undisclosed - 7/25/25 |
Tomlinson is on the injured reserve list due to an undisclosed injury, and is expected to be sidelined for the entire season. |
| Player |
|
Status/Updated |
Notes |
| Jordan Howden
|
DB |
Ques Sept. 14 - Oblique - 9/7/25 |
Howden is nursing with a oblique injury, and it has yet to be established if he will be active against the 49ers on Sunday, September 14th. |
| Chase Young
|
DE |
Ques Sept. 14 - Calf - 9/7/25 |
Young is bothered by a calf injury, and it is unknown if he will be active against 49ers on Sunday, September 14th. |
| Khristian Boyd
|
DT |
Ques Sept. 14 - Hand - 9/7/25 |
Boyd is dealing with a hand injury, and it is unknown if he will be active against the 49ers on Sunday, September 14th. |
| Taliese Fuaga
|
OT |
Ques Sept. 14 - Knee - 9/7/25 |
Fuaga left the game due to a knee injury, and it has yet to be established if he will be active against the 49ers on Sunday, September 14th. |
| Zach Wood
|
LS |
Ques Sept. 14 - Hamstring - 9/7/25 |
Wood is dealing with a hamstring injury, and it remains to be seen if he will be in the lineup against 49ers on Sunday, September 14th. |
| Trevor Penning
|
OT |
Ques Sept. 14 - Toe - 9/7/25 |
Penning is bothered by a toe injury, and it is uncertain if he will be active against 49ers on Sunday, September 14th. |
| Barry Wesley
|
OT |
Out indefinitely - Undisclosed - 8/26/25 |
Wesley is placed on the injured reserve list with an undisclosed injury, and team officials have yet to provide an exact return date. |
| Landon Young
|
OT |
Out indefinitely - Ankle - 8/26/25 |
Young has been added to the injured reserve list with an ankle injury, and it is unknown how long he will be debilitated. |
| Will Clapp
|
C |
Out indefinitely - Foot - 8/12/25 |
Clapp is placed on the injured reserve list with a foot injury, and he will miss an extended period. |
| Bub Means
|
WR |
Out indefinitely - Leg - 8/13/25 |
Means is placed on the injured reserve list with a lower leg injury, and he will miss an extended period. |
| John Ridgeway III
|
DT |
Early Oct - Pectoral - 8/26/25 |
Ridgeway III has hit the injured list with a pectoral injury, and he will be out of action till early October. |
| Taysom Hill
|
TE |
Out indefinitely - Knee - 8/28/25 |
Hill has been placed on the PUP list while recovering from a torn acl, and team officials have yet to provide an exact return date. |
| Foster Moreau
|
TE |
Out indefinitely - Knee - 8/28/25 |
Moreau has landed on the PUP list with a knee injury, and it is unclear how long he will be idle. |
| Nick Saldiveri
|
OL |
Out indefinitely - Knee - 8/3/25 |
Saldiveri is placed on the injured reserved list due to a knee injury, and it is unknown how long he will be debilitated. |
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