Pittsburgh 2, Toronto 1
Johan Oviedo struck out six batters over five innings and combined with three relievers on a three-hitter, leading the host Pittsburgh Pirates to a 2-1 victory over the Toronto Blue Jays on Wednesday afternoon.
Philadelphia 11, Seattle 2
Kyle Schwarber doubled, homered and had five RBIs, giving him an MLB-leading 109 this season, as the Philadelphia Phillies defeated the visiting Seattle Mariners 11-2 on Wednesday afternoon to complete a three-game sweep.
Detroit 7, Houston 2
Dillon Dingler had an RBI triple during a six-run first inning and the host Detroit Tigers completed a three-game sweep of the Houston Astros with a 7-2 victory on Wednesday afternoon.
Arizona 3, Cleveland 2
Adrian Del Castillo singled in the winning run in the 10th inning after Lourdes Gurriel Jr. homered to tie the game in the ninth, and the Arizona Diamondbacks beat the Cleveland Guardians 3-2 on Wednesday afternoon in Phoenix.
Miami 6, St. Louis 2
Sandy Alcantara pitched seven strong innings against the franchise that signed him as the host Miami Marlins defeated the St. Louis Cardinals 6-2 on Wednesday night.
Washington 5, NY Mets 4
Josh Bell homered and drove in two runs to help lift the host Washington Nationals to a 5-4 victory over the New York Mets on Wednesday.
Atlanta 1, Chi. White Sox 0
Hurston Waldrep threw a career-best seven scoreless innings and the Atlanta Braves beat the visiting Chicago White Sox 1-0 on Wednesday in the rubber game of their three-game interleague series.
NY Yankees 6, Tampa Bay 4
Giancarlo Stanton hit a pinch-hit two-run homer in the 10th inning as the visiting New York Yankees completed a perfect five-game road trip Wednesday night with a 6-4 win over the Tampa Bay Rays.
Texas 6, Kansas City 3
Kyle Higashioka delivered a two-out, three-run double in the ninth inning and the visiting Texas Rangers earned a needed 6-3 victory over the Kansas City Royals on Wednesday night.
Athletics 4, Minnesota 2
Shea Langeliers belted a tiebreaking two-run homer in the top of the 10th inning and the Athletics held on for a 4-2 win over the Minnesota Twins on Wednesday night in Minneapolis.
Chi. Cubs 4, Milwaukee 3
Michael Busch hit a bases-clearing double and Daniel Palencia stranded the bases loaded in the ninth inning as the Chicago Cubs beat the visiting Milwaukee Brewers 4-3 on Wednesday.
Colorado 8, LA Dodgers 3
Hunter Goodman had three hits and three RBIs, Jordan Beck also had three hits, and the Colorado Rockies got six solid innings from Tanner Gordon to beat the Los Angeles Dodgers 8-3 in Denver on Wednesday night.
LA Angels 2, Cincinnati 1
Luis Rengifo drove in the go-ahead run in the eighth inning and Yusei Kikuchi allowed one run on seven hits over seven innings as the Los Angeles Angels snapped a 10-game losing streak to the Cincinnati Reds with a 2-1 victory on Wednesday night in Anaheim, Calif.
San Diego 8, San Francisco 1
Gavin Sheets homered twice and JP Sears earned his first win with the San Diego Padres in their 8-1 rout of the visiting San Francisco Giants on Wednesday night.