Pittsburgh 3, Cincinnati 2
Bryan Reynolds' two-out triple in the bottom of the eighth drove in the tying and go-ahead runs and led the host Pittsburgh Pirates to a 3-2 comeback win over the Cincinnati Reds on Friday night.
Baltimore 3, Athletics 2
Adley Rutschman and Ryan Mountcastle hit back-to-back home runs in the first inning and the Baltimore Orioles held on to nip the visiting Athletics 3-2 in a series opener Friday night.
Houston 5, NY Yankees 3
Carlos Correa snapped a tie with a leadoff single in the 10th inning and Taylor Trammell hit a two-run homer later in the frame as the Houston Astros earned a 5-3 victory over the host New York Yankees on Friday night.
Detroit 6, LA Angels 5
Matt Vierling delivered a pinch-hit, three-run homer in the eighth as the host Detroit Tigers rallied for a 6-5 win over the Los Angeles Angels on Friday night.
Miami 5, Atlanta 1
Edward Cabrera struck out a season-high 11 and gave up just two hits while pitching the Miami Marlins to a 5-1 win over the host Atlanta Braves on Friday night.
Cleveland 9, Chi. White Sox 5
Carlos Santana had four RBIs, C.J. Kayfus doubled twice and drove in three runs, and the visiting Cleveland Guardians opened a three-game series against the Chicago White Sox with a 9-5 win on Friday.
Philadelphia 9, Texas 1
Kyle Schwarber, Brandon Marsh and Trea Turner clubbed home runs to back six strong innings from Cristopher Sanchez as the Philadelphia Phillies romped past the Texas Rangers 9-1 on Friday in Arlington, Texas.
Milwaukee 3, NY Mets 2
Brice Turang hit a two-run homer and Brandon Woodruff tossed seven effective innings as the Milwaukee Brewers extended their winning streak to seven games with a 3-2 comeback victory over the visiting New York Mets on Friday.
Minnesota 9, Kansas City 4
Ryan Jeffers went 3-for-4 with two RBIs and the Minnesota Twins pulled away for a 9-4 win over the Kansas City Royals on Friday night in Minneapolis.
St. Louis 5, Chi. Cubs 0
Michael McGreevy and three relievers scattered seven hits as the St. Louis Cardinals blanked the visiting Chicago Cubs 5-0 Friday night.
Arizona 6, Colorado 1
Corbin Carroll and Blaze Alexander homered, Zac Gallen pitched six strong innings, and the Arizona Diamondbacks beat the Colorado Rockies 6-1 in the opener of a three-game series in Phoenix on Friday.
Boston 10, San Diego 2
Wilyer Abreu and Masataka Yoshida belted two-run homers and Walker Buehler tossed six scoreless innings as the visiting Boston Red Sox stopped the San Diego Padres 10-2 on Friday.
Seattle 3, Tampa Bay 2
Cal Raleigh hit his major-league-leading 43rd homer of the season as the Seattle Mariners rallied to defeat the visiting Tampa Bay Rays 3-2 on Friday in the opener of a three-game series.
LA Dodgers 5, Toronto 1
Los Angeles Dodgers left-hander Clayton Kershaw took on fellow future Hall of Famer Max Scherzer of the Toronto Blue Jays on Friday night and earned the victory with help from Mookie Betts.
San Francisco 5, Washington 0
Rafael Devers and Casey Schmitt hit home runs, Kai-Wei Teng recorded his first major league win and the San Francisco Giants opened a key nine-game homestand with a 5-0 victory over the Washington Nationals on Friday night.