San Francisco at Pittsburgh 12:35 PM ET
San Francisco's Robbie Ray will oppose Pittsburgh's Andrew Heaney in a matchup of veteran lefties on Wednesday afternoon when the Giants and the host Pirates play the rubber match of a three-game series.
Baltimore at Philadelphia 12:35 PM ET
The Philadelphia Phillies are beginning to create a bit of separation in the National League East.
Cleveland at NY Mets 1:10 PM ET
a day that ended with the New York Mets a half-game out of first place in the National League East and comfortably in the second NL wild-card position.
Minnesota at Detroit 1:10 PM ET
The Detroit Tigers added two starting pitchers, Chris Paddack and Charlie Morton, last week prior to the trade deadline. Getting consistently strong outings out of veteran right-hander Jack Flaherty is just as important.
Cincinnati at Chi. Cubs 2:20 PM ET
Chicago Cubs rookie right-hander Cade Horton has been downright stingy of late.
NY Yankees at Texas 2:35 PM ET
The Texas Rangers will vie for a sweep of the slumping New York Yankees when the teams square off on Wednesday afternoon in the finale of a three-game series in Arlington, Texas.
Toronto at Colorado 3:10 PM ET
Denver has a reputation for being kind to baseball hitters, but the metro area also has produced some quality pitchers.
Tampa Bay at LA Angels 4:07 PM ET
Two teams battling to keep their American League wild-card hopes alive will turn to starting pitchers in the midst of long winless streaks Wednesday afternoon when the Tampa Bay Rays face the Los Angeles Angels in the rubber game of their three-game series in Anaheim, Calif.
St. Louis at LA Dodgers 4:10 PM ET
A week after Shohei Ohtani sent a scare throughout Los Angeles when he departed early from his latest pitching performance, the right-hander will return to the mound on Wednesday afternoon in the Dodgers' series finale against the visiting St. Louis Cardinals.
Houston at Miami 4:40 PM ET
With 15 runs in their last two games, the Houston Astros will bid for a series sweep over the host Miami Marlins on Wednesday afternoon.
Athletics at Washington 6:45 PM ET
The Washington Nationals have been outscored 54-21 over their past four games and will try to end a six-game losing streak when they host the Athletics on Wednesday evening.
Kansas City at Boston 7:10 PM ET
When the Red Sox host the Kansas City Royals in the finale of a three-game series on Wednesday night, one of Boston's newest acquisitions will take on a former one with a sweep on the line.
Milwaukee at Atlanta 7:15 PM ET
Jose Quintana wasn't even sure he was going to be with Milwaukee before the trade deadline expired last week. Now he'll be on the mound Wednesday night when the Brewers try to sweep a three-game series and complete an undefeated road trip.
San Diego at Arizona 9:40 PM ET
When left-hander Nestor Cortes joined San Diego at the trade deadline last week, he marveled at the bullpen that general manager A.J. Preller had assembled.
Chi. White Sox at Seattle 9:40 PM ET
Eugenio Suarez and Josh Naylor showed what they can add to the Seattle Mariners' offense.