Miami at Milwaukee 4:10 PM ET
The Milwaukee Brewers won their final seven games before the All-Star break and have not cooled off upon their return, winning five of six to take over first place in the National League Central.
Arizona at Pittsburgh 6:40 PM ET
The Arizona Diamondbacks are slipping out of the playoff race and will attempt to gain some traction when they hit the road to face the surging Pittsburgh Pirates in the opener of a three-game series Friday.
Philadelphia at NY Yankees 7:05 PM ET
Bryce Harper and Aaron Judge recently reached 350 career homers, not that the impressive milestones have kept their respective teams in first place of their divisions.
Colorado at Baltimore 7:05 PM ET
The Baltimore Orioles ought to have a somewhat rosy outlook after winning again.
Toronto at Detroit 7:10 PM ET
The Toronto Blue Jays didn't cool off in their first road game since the All-Star break, rolling to an 11-4 victory over the Detroit Tigers on Thursday.
LA Dodgers at Boston 7:10 PM ET
The Los Angeles Dodgers will be without a key piece of their lineup Friday when they begin a nine-game road trip by opening a three-game series against the Boston Red Sox.
Tampa Bay at Cincinnati 7:10 PM ET
Two clubs in nearly identical positions in the playoff chase and with identical records meet on Friday when the Tampa Bay Rays visit the Cincinnati Reds in the opener of a three-game series.
San Diego at St. Louis 7:15 PM ET
The St. Louis Cardinals are trying to regain traction in the National League wild-card race after enduring a lengthy slide.
Chi. Cubs at Chi. White Sox 7:40 PM ET
Left-hander Shota Imanaga was on the injured list with a strained left hamstring when the Chicago Cubs swept the visiting White Sox from May 16-18.
Atlanta at Texas 8:05 PM ET
The Texas Rangers will look to build on their hot start to the second half of the season when they host the swooning Atlanta Braves on Friday in the opener of a three-game interleague series in Arlington, Texas.
Athletics at Houston 8:10 PM ET
One of the foremost challenges facing Houston Astros manager Joe Espada and his injury-strapped roster is utilizing the revolving door of players recalled from the minors or acquired off waivers.
Washington at Minnesota 8:10 PM ET
A feeling of uncertainty hangs over the Minnesota Twins as they return home to open a three-game series against the Washington Nationals on Friday night in Minneapolis.
Seattle at LA Angels 9:38 PM ET
All things considered, the Seattle Mariners probably couldn't have asked for a better start to their seven-game road trip leading into the trade deadline.
NY Mets at San Francisco 10:15 PM ET
Rafael Devers and Juan Soto get an opportunity to reintroduce themselves to familiar foes for their new teams when the New York Mets open a three-game road series against the San Francisco Giants on Friday night.