Washington at Pittsburgh 6:40 PM ET
After the slumping Pittsburgh offense finally broke through, the Pirates will try to keep the momentum going against the visiting Washington Nationals on Tuesday night.
Seattle at Cincinnati 6:40 PM ET
The Cincinnati Reds welcome their former ace Luis Castillo back home Tuesday night when they open a three-game series with the visiting Seattle Mariners.
Arizona at Miami 6:40 PM ET
The Arizona Diamondbacks, who have won four of their past five contests, will start a three-game series against the host Miami Marlins on Tuesday night.
San Francisco at Philadelphia 6:45 PM ET
Justin Verlander hasn't been at his best this season, but perhaps a matchup with the scuffling Philadelphia Phillies could prove to be the cure.
Cleveland at Baltimore 7:05 PM ET
The Baltimore Orioles want to change the results, but they're not looking for a complete makeover.
Boston at Tampa Bay 7:05 PM ET
The Tampa Bay Rays' offense was unreliable until it went off in Monday's 16-1 blowout of the visiting Boston Red Sox.
Kansas City at NY Yankees 7:05 PM ET
The New York Yankees saw their power turn sporadic for most of the past week until Monday.
Atlanta at Toronto 7:07 PM ET
Toronto Blue Jays first baseman Vladimir Guerrero Jr. has a new, huge contract but no home runs.
NY Mets at Minnesota 7:40 PM ET
Pete Alonso waited for much of the offseason without knowing where he would play in 2025.
Athletics at Chi. White Sox 7:40 PM ET
Athletics left-hander Jeffrey Springs faltered when he faced the Chicago Cubs at the start of April.
Detroit at Milwaukee 7:40 PM ET
The gauntlet of opposing starters will continue for the Milwaukee Brewers when they host the Detroit Tigers and right-hander Jack Flaherty on Tuesday night in the middle game of a three-games series.
Houston at St. Louis 7:45 PM ET
The St. Louis Cardinals have climbed back to .500 by winning four of their last six games.
LA Angels at Texas 8:05 PM ET
The Los Angeles Angels and Texas Rangers both want to get back on the winning path when they square off Tuesday in the opener of a three-game American League West series in Arlington, Texas.
Chi. Cubs at San Diego 9:40 PM ET
It took until late July last year for the San Diego Padres to hit their stride.
Colorado at LA Dodgers 10:10 PM ET
After three consecutive series defeats, the Los Angeles Dodgers will be out to end their skid when they host the Colorado Rockies on Tuesday night.